I have Outlook 2016 installed on Windows 10 64-bit system and it worked fine so far. Yesterday I went to open it and got the following error message:
â€œCan’t start Microsoft Outlook. Can’t open Outlook window. ”
The sad thing is that I had this EXACT same issue in Outlook 2010 and even wrote an article about it over a year ago:
For some reason, the solution to the problem in Outlook 2010 is different and none of these methods worked for me when I tried to fix it in 2016. Read the previous post and if nothing works for you, try the methods listed below.
First method – delete the registry key
Click Start and type regedit to open the Registry Editor in Windows.
Navigate to the following registry key:
HKEY_CURRENT_USER Software Microsoft Windows NT CurrentVersion Windows Messaging Subsystem
Now delete the profiles key that is in the Windows messaging engine. Restart your computer and try opening Outlook 2010. Hope this solves your problem!
Method 2 – Install the latest service pack and Microsoft updates
The next thing you can try, if that didn’t work for you, is to install the latest Office updates. You can do this by opening any Office program and clicking File – Account. On the right, you will see production information. Beneath it there is a section called “Office Updates”. Click the Update button and select Update Now.
This fixed the issue for quite a few people, so if nothing works for you, be sure to install the latest Office and Windows updates.
Method 3 – Open Task Manager / Kill Process
This issue with Outlook not starting can also be caused by multiple instances of Outlook running without properly shutting down. If you go into Task Manager (Ctrl + Shift + Esc), you should only see one Outlook process running.
If you see more than one outlook.exe in the list of processes, select each one and click End Process. After you have finished all Outlook processes, try restarting Outlook and see if it loads correctly.
So, you have a couple more possible solutions to this very annoying problem! If you find another solution, please leave a comment here and let us know! Enjoy!